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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RDBP All Species: 25.45
Human Site: S124 Identified Species: 70
UniProt: P18615 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18615 NP_002895.3 380 43240 S124 D D D L Q E S S R R P Q R K S
Chimpanzee Pan troglodytes XP_527349 377 42875 S119 D D D L Q E S S R H P Q R K S
Rhesus Macaque Macaca mulatta XP_001113859 380 43189 S124 D D D L Q E S S R R P Q R K S
Dog Lupus familis XP_532087 374 42309 S124 D D D L Q E S S R R P Q R K S
Cat Felis silvestris
Mouse Mus musculus P19426 375 42536 S124 D E D L Q E P S R R P Q R K S
Rat Rattus norvegicus NP_997713 369 41754 S124 D E D L Q E P S R R P Q R K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001089853 335 38349 S124 D E E Q A E A S R R S Q R K S
Zebra Danio Brachydanio rerio NP_001002375 346 39718 A124 D E E P P D S A K R I H R K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P92204 280 31792 D79 I Q K Q T K Q D Q T S F K R P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.6 99.2 94.7 N.A. 91.5 91.3 N.A. N.A. N.A. 64.2 65.2 N.A. 29.2 N.A. N.A. N.A.
Protein Similarity: 100 98.1 100 97.3 N.A. 94.4 94.7 N.A. N.A. N.A. 76.3 76.8 N.A. 47.3 N.A. N.A. N.A.
P-Site Identity: 100 93.3 100 100 N.A. 86.6 86.6 N.A. N.A. N.A. 60 40 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 93.3 100 100 N.A. 93.3 93.3 N.A. N.A. N.A. 80 73.3 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 12 0 12 12 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 89 45 67 0 0 12 0 12 0 0 0 0 0 0 0 % D
% Glu: 0 45 23 0 0 78 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 12 0 12 0 0 0 % H
% Ile: 12 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % I
% Lys: 0 0 12 0 0 12 0 0 12 0 0 0 12 89 0 % K
% Leu: 0 0 0 67 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 12 12 0 23 0 0 0 67 0 0 0 12 % P
% Gln: 0 12 0 23 67 0 12 0 12 0 0 78 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 78 78 0 0 89 12 0 % R
% Ser: 0 0 0 0 0 0 56 78 0 0 23 0 0 0 89 % S
% Thr: 0 0 0 0 12 0 0 0 0 12 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _